IL-8 α<sub>1</sub>-Adrenergic Receptors and LUTS
نویسندگان
چکیده
منابع مشابه
Induction of functional IL-8 receptors by IL-4 and IL-13 in human monocytes.
IL-8 and related Glu-Leu-Arg (ELR+) CXC chemokines are potent chemoattractants for neutrophils but not for monocytes. IL-13 and IL-4 strongly increased CXCR1 and CXCR2 chemokine receptor expression in human monocytes, macrophages, and dendritic cells. The effect was receptor- and cell type-selective, in that CCRs were not increased and no augmentation was seen in neutrophils. The effect was rap...
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Platinum based drugs are the cornerstone of chemotherapy for ovarian cancer, however the development of chemoresistance hinders its success. IL-8 is involved in regulating several pro-survival pathways in cancer. We studied the expression of IL-8 and IL-8 receptors in platinum sensitive and resistant cell lines. Using qRT-PCR and immunohistochemistry, both platinum sensitive (PEA1, PEO14) and r...
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Neurons in the paraventricular nucleus (PVN) that project to the brainstem and spinal cord are important for autonomic regulation. The excitability of pre-autonomic PVN neurons is controlled by the noradrenergic input from the brainstem. In this study, we determined the role of " 2 adrenergic receptors in the regulation of excitatory and inhibitory synaptic inputs to spinally projecting PVN neu...
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It is well known that the renal nerve plays an important role in the regulation of renal functions such as sodium and water reabsorption in the tubules as well as in the pathogenesis of essential hypertension. The renal sympathetic nerves innervate to the basement membranes of almost all nephron segments. Specific adrenergic receptors and intracellular signal transduction systems are located in...
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Background: IGF-1 and certain other cytokines have been shown to exert inflammatory/anti-inflammatory roles in chronic joint diseases. Objective: To assess the effect of IGF-1, IL-27 and IL-35, their interaction and their receptor expression in a rheumatoid arthritis model. Methods: Freund’s adjuvant-induced chronic joint inflammation was operated on 160 male rats. Animals were divided into his...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 2007
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol.98.61